The defence ministry in Niger says hundreds of jihadists have attacked a military post in the southern region of Diffa.
Sixteen soldiers were killed and nine wounded, it said.
The army counter-attacked, killing 50 members of the Boko Haram militant group.
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The insurgents regularly cross over from neighbouring Nigeria.
Earlier, the army in Niger said it had killed about 100 jihadists in the south-west of the country, near the border with Burkina Faso.
Islamist violence is intensifying in the Sahel, especially in the border area between Niger, Mali and Burkina Faso.
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